Protein and GLP-1s
- Sean Duffy
- Jun 12
- 2 min read
Protein Guide for Patients Taking GLP-1 Medications
Compass Direct Care
Sean P. Duffy, DO
(Mounjaro®, Zepbound®, Wegovy®, Ozempic®, Saxenda®)
Why Protein Matters
GLP-1 medications help reduce appetite and promote weight loss. However, rapid weight loss can result in loss of muscle mass if protein intake is inadequate.
Our goal is to lose fat—not muscle.
Adequate protein intake helps:
✓ Preserve muscle mass
✓ Improve metabolism
✓ Reduce hunger
✓ Increase satiety
✓ Support healthy aging
✓ Improve strength and energy
How Much Protein Do I Need?
General Goal
Aim for:
80–120 grams of protein daily
Most adults should target:
25–40 grams of protein at each meal
Protein-First Rule
Before eating carbohydrates or snacks, ask:
“Where is my protein?”
Build every meal around a protein source first.
Excellent Protein Sources
Poultry and Seafood
✓ Chicken breast (3 oz = 26 g)
✓ Turkey breast (3 oz = 25 g)
✓ Salmon (4 oz = 25 g)
✓ Tuna (4 oz = 25 g)
✓ Shrimp (4 oz = 24 g)
✓ Cod (4 oz = 20 g)
Eggs and Dairy
✓ Eggs (2 eggs = 12 g)
✓ Greek yogurt (1 cup = 18–20 g)
✓ Cottage cheese (1 cup = 25 g)
✓ String cheese = 7 g
✓ Fairlife® milk (1 cup = 13 g)
Plant Proteins
✓ Lentils (1 cup = 18 g)
✓ Black beans (1 cup = 15 g)
✓ Chickpeas (1 cup = 14 g)
✓ Edamame (1 cup = 18 g)
✓ Tofu (½ block = 20 g)
Convenient Protein Options
✓ Protein shakes (20–30 g)
✓ Protein bars (15–20 g)
✓ Rotisserie chicken
✓ Tuna packets
✓ Hard-boiled eggs
✓ Greek yogurt cups
Easy Protein Goals
Breakfast
25–30 grams
Lunch
25–35 grams
Dinner
30–40 grams
Snack
10–20 grams
Daily Total
80–120 grams
Sample High-Protein Day
Breakfast
Greek yogurt with berries
2 eggs
Protein = 30 grams
Lunch
Grilled chicken salad with olive oil vinaigrette
Protein = 35 grams
Snack
Protein shake
Protein = 30 grams
Dinner
Salmon with vegetables and quinoa
Protein = 35 grams
Daily Total
Approximately 100–110 grams
Managing Common GLP-1 Side Effects
Nausea
• Eat slowly
• Choose smaller meals
• Avoid greasy foods
• Stay hydrated
Constipation
• Increase water intake
• Increase vegetables and fruit
• Increase fiber gradually
• Stay active
Reduced Appetite
Even if you are not hungry:
✓ Eat protein first
✓ Do not skip meals
✓ Consider a protein shake if needed
Strength Training Matters
Weight loss should focus on losing fat while preserving muscle.
Aim for:
Resistance exercise 2–4 days per week
Examples include:
✓ Walking
✓ Bodyweight exercises
✓ Resistance bands
✓ Free weights
✓ Strength machines
Progress Over Perfection
Healthy habits practiced consistently lead to better results than strict dieting.
The goal is not to eat perfectly.
The goal is to build habits that you can maintain for life.
Questions?
Sean P. Duffy, DO
273 Peninsula Farm Rd, Suite D
Arnold, MD 21012
410-699-9692
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